EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   2.7.1.154 | Fibrosarcoma |
17611681 |
3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
1
1
0 |
| 2.7.1.154 | Carcinoma, Hepatocellular |
24055031 |
A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 2.7.1.154 | Hepatitis C |
24055031 |
A class II phosphoinositide 3-kinase plays an indispensable role in hepatitis C virus replication. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 2.7.1.154 | Neoplasms |
30591513 |
A high-avidity biosensor reveals plasma membrane PI(3,4)P2 is predominantly a class I PI3K signaling product. |
unassigned |
0 |
| 2.7.1.154 | Neoplasms |
31632439 |
A Novel Prognostic Signature of Transcription Factors for the Prediction in Patients With GBM. |
causal interaction
unassigned |
3
0 |
| 2.7.1.154 | Neoplasms |
28743532 |
A synthetic peptide hijacks the catalytic subunit of class I PI3K to suppress the growth of cancer cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
1
4 |
| 2.7.1.154 | Carcinogenesis |
18270679 |
Activation of phosphoinositide 3-kinase by the NBS1 DNA repair protein through a novel activation motif. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 2.7.1.154 | Neoplasms |
31176568 |
Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 2.7.1.154 | Breast Neoplasms |
25368680 |
Amplification of Chromosome 1q Genes Encoding the Phosphoinositide Signalling Enzymes PI4KB, AKT3, PIP5K1A and PI3KC2B in Breast Cancer. |
causal interaction
unassigned |
3
0 |
| 2.7.1.154 | Neoplasms |
31638167 |
Analyses of FGFR3 and PIK3CA mutations in neuroblastomas and the effects of the corresponding inhibitors on neuroblastoma cell lines. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
2
4
3 |
