EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    2.4.1.11 | Alzheimer Disease |
33517657 |
((E)-N-(4-(((2-Amino-5-phenylpyridin-3-yl)imino)methyl)pyridin-2-yl)cyclopropanecarboxamide) Ameliorated A?1-42-Induced Alzheimer's Disease in SD Rats by Inhibiting Oxidative Stress and Apoptosis. |
ongoing research
unassigned |
4
0 |
| 2.4.1.11 | Diabetes Mellitus |
21988345 |
(WO2011057959) indole and indazole derivatives as glycogen synthase activators: a patent evaluation. |
therapeutic application
unassigned |
1
0 |
| 2.4.1.11 | Diabetes Mellitus, Type 2 |
21988345 |
(WO2011057959) indole and indazole derivatives as glycogen synthase activators: a patent evaluation. |
therapeutic application
unassigned |
1
0 |
| 2.4.1.11 | Melanoma |
29028954 |
1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/?-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M. |
causal interaction
unassigned |
1
0 |
| 2.4.1.11 | Neoplasms |
29028954 |
1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/?-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M. |
causal interaction
unassigned |
1
0 |
| 2.4.1.11 | Neoplasms |
28743492 |
5-Bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase. |
therapeutic application
unassigned |
1
0 |
| 2.4.1.11 | Neuroblastoma |
29846250 |
9-ING-41, a small-molecule glycogen synthase kinase-3 inhibitor, is active in neuroblastoma. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.4.1.11 | Lymphoma, B-Cell |
24425042 |
?-eleostearic acid inhibits growth and induces apoptosis in breast cancer cells via HER2/HER3 signaling. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 2.4.1.11 | Neoplasms |
31026007 |
?-Thujaplicin inhibits basal-like mammary tumor growth by regulating glycogen synthase kinase-3?/?-catenin signaling. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.4.1.11 | Diabetes Mellitus, Type 2 |
11408400 |
A defect in glycogen synthesis characterizes insulin resistance in hypertensive patients with type 2 diabetes. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
2
0 |
