EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.8.1.4 | dihydrolipoyl dehydrogenase deficiency |
3104678 |
A decrease in glycine cleavage activity in the liver of a patient with dihydrolipoyl dehydrogenase deficiency. |
causal interaction
unassigned |
3
0 |
| 1.8.1.4 | Acidosis, Lactic |
643378 |
A defect in branched-chain amino acid metabolism in a patient with congenital lactic acidosis due to dihydrolipoyl dehydrogenase deficiency. |
causal interaction
unassigned |
4
0 |
| 1.8.1.4 | dihydrolipoyl dehydrogenase deficiency |
643378 |
A defect in branched-chain amino acid metabolism in a patient with congenital lactic acidosis due to dihydrolipoyl dehydrogenase deficiency. |
causal interaction
unassigned |
4
0 |
| 1.8.1.4 | Alzheimer Disease |
23173729 |
A metabolic signature for long life in the Caenorhabditis elegans Mit mutants. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 1.8.1.4 | oxoglutarate dehydrogenase (succinyl-transferring) deficiency |
15712224 |
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. |
causal interaction
unassigned |
4
0 |
| 1.8.1.4 | Ischemic Stroke |
29017857 |
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury. |
causal interaction
unassigned |
4
0 |
| 1.8.1.4 | Stroke |
29017857 |
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury. |
causal interaction
unassigned |
4
0 |
| 1.8.1.4 | Hepatitis B |
20801029 |
Affibody-displaying bionanocapsules for specific drug delivery to HER2-expressing cancer cells. |
unassigned |
0 |
| 1.8.1.4 | Alzheimer Disease |
4004169 |
An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
2
2
0 |
| 1.8.1.4 | Ataxia |
6893466 |
An investigation of pyruvate metabolism in patients with cerebellar and spinocerebellar degeneration. |
diagnostic usage
ongoing research
unassigned |
2
1
0 |
