EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   1.13.11.24 | Melanoma |
20711196 |
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
4
0 |
| 1.13.11.24 | Pulmonary Disease, Chronic Obstructive |
19378221 |
Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice. |
causal interaction
unassigned |
4
0 |
| 1.13.11.24 | Neoplasms |
24390086 |
Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element. |
ongoing research
unassigned |
1
0 |
| 1.13.11.24 | Lymphoma, B-Cell |
14573596 |
Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. |
causal interaction
unassigned |
1
0 |
| 1.13.11.24 | Carcinoma |
31436299 |
Curcumin decreases epithelial?mesenchymal transition by a Pirin?dependent mechanism in cervical cancer cells. |
ongoing research
therapeutic application
unassigned |
2
4
0 |
| 1.13.11.24 | Uterine Cervical Neoplasms |
31436299 |
Curcumin decreases epithelial?mesenchymal transition by a Pirin?dependent mechanism in cervical cancer cells. |
ongoing research
therapeutic application
unassigned |
2
4
0 |
| 1.13.11.24 | Neoplasms |
15547752 |
Gene expression in response to anti-tumour intervention by polysaccharide-K (PSK) in colorectal carcinoma cells. |
diagnostic usage
therapeutic application
unassigned |
3
3
0 |
| 1.13.11.24 | Breast Neoplasms |
23374458 |
High levels of ?-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
| 1.13.11.24 | Neoplasms |
32679705 |
Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-?B Activation in Oral Cancer Cells. |
causal interaction
ongoing research
unassigned |
1
2
0 |
| 1.13.11.24 | Breast Neoplasms |
34262943 |
Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study. |
therapeutic application
unassigned |
1
0 |
