EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
3.4.24.27 | 0.0000115 |
- |
3-phenyl-2-(trifluoromethyl) quinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.0002477 |
- |
3-(isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.00125 |
- |
2-ethylquinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.008 |
- |
2-[benzyl[2-(hydroxyamino)-2-oxoethyl]amino]-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide (non-preferred name) |
pH 7.5, 37°C |
733787 |
3.4.24.27 | 0.012 |
- |
2-[benzyl[2-(hydroxyamino)-2-oxoethyl]amino]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide (non-preferred name) |
pH 7.5, 37°C |
733787 |
3.4.24.27 | 0.01832 |
- |
3-([(1E)-[4-(dimethylamino) phenyl]methylene]amino)-2-methylquinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.03786 |
- |
3-amino-2-(trifluoromethyl) quinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.04203 |
- |
3-([(1E)-[4-(dimethylamino) phenyl]methylene]amino)-2-phenylquinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.05489 |
- |
3-amino-2-methylquinazolin-4(3H)-one |
at pH 7.0 and 25°C |
711460 |
3.4.24.27 | 0.067 |
- |
2-[(biphenyl-4-ylsulfonyl)[2-(hydroxyamino)-2-oxoethyl]amino]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide (non-preferred name) |
pH 7.5, 37°C |
733787 |