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EC Number IC50 Value IC50 Value Maximum Inhibitor Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - more IC50 concentration of the aza-peptide Michael acceptor Aza-Asn-11a in a range of about 500 nM determined 683572
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - more inhibitory doses for 50% proteinase activity inhibition higher for root legumain activity than for endosperm one 679859
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N-[(2S)-1-{2-(2-amino-2-oxoethyl)-2-[(2E)-4-oxo-4-phenylbut-2-enoyl]hydrazinyl}-1-oxopropan-2-yl]-N2-[(benzyloxy)carbonyl]-L-alaninamide IC50 is above 0.01 mM, in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N-[(2S)-1-{2-(2-amino-2-oxoethyl)-2-[(2E)-4-oxo-4-phenylbut-2-enoyl]hydrazinyl}-1-oxopropan-2-yl]-N2-[(benzyloxy)carbonyl]-L-alaninamide IC50 is above 0.02 mM, 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 5.5, 0.1 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N-[(2S)-1-{2-(2-amino-2-oxoethyl)-2-[(2E)-4-oxo-4-phenylbut-2-enoyl]hydrazinyl}-1-oxopropan-2-yl]-N2-[(benzyloxy)carbonyl]-L-alaninamide no inhibition after 20 min of preincubation with inhibitor in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N-[(2S)-1-{2-(2-amino-2-oxoethyl)-2-[(2E,4E)-hexa-2,4-dienoyl]hydrazinyl}-1-oxopropan-2-yl]-N2-[(benzyloxy)carbonyl]-L-alaninamide no inhibition after 20 min of preincubation with inhibitor in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N2-(N-benzyloxycarbonylalanylalanyl)-N1-carbamoylmethyl-N1-trans-(3-(2-furyl)propenoyl)hydrazine IC50 is above 0.002 mM, in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N2-(N-benzyloxycarbonylalanylalanyl)-N1-carbamoylmethyl-N1-trans-(3-(3-pyridyl)propenoyl)hydrazine IC50 is above 0.002 mM, in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N2-(N-benzyloxycarbonylalanylalanyl)-N1-carbamoylmethyl-N1-trans-(3-(3-pyridyl)propenoyl)hydrazine IC50 is above 0.15 mM, 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 5.5, 0.1 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34-999 - N2-(N-benzyloxycarbonylalanylalanyl)-N1-carbamoylmethyl-N1-trans-(3-(methyl-1-naphthylmethylcarbamoyl)propenoyl)hydrazine IC50 is below 0.000001 mM, in 0.1 M citrate phosphate, 4 mM dithiothreitol, pH 6.8, 0.01 mM Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin as substrate 699430
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