EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
1.1.1.213 | 0.000735 |
- |
indomethacin |
competitive, IC50 for reduction of 9,10-phenanthrenequinone by NADPH at pH6.0 is 0.000735 mM |
347982 |
1.1.1.213 | 0.00333 |
- |
indomethacin |
competitive, IC50 for oxidation of androsterone by NAD+ at pH 7.0 0.00333 mM |
347982 |
1.1.1.213 | 0.0004 |
- |
Phenolphthalein |
AKR1C4-selective inhibitor, in vitro and in vivo inhibition, IC50: 0.0004 mM |
675595 |
1.1.1.213 | 1.084 |
- |
Flufenamic acid |
a nonsteroidalanti-inflammatory drug, IC50: 1.084 mM |
675595 |
1.1.1.213 | 0.000049 |
- |
ursodeoxycholate |
natural inhibitor, in vivo IC50: 0.00024 mM in fluorometric assay, 0.00014 mM in radiometric assay, in vitro IC50: 0.000049 mM in fluorometric assay |
676812 |
1.1.1.213 | 0.00031 |
- |
Flufenamic acid |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.0040 mM in fluorometric assay, in vitro IC50: 0.00031 mM in fluorometric assay |
676812 |
1.1.1.213 | 0.0027 |
- |
naproxen |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.0094 mM in fluorometric assay, 0.016 mM in radiometric assay, in vitro IC50: 0.0027 mM in fluorometric assay |
676812 |
1.1.1.213 | 0.009 |
- |
Ibuprofen |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.017 mM in fluorometric assay, in vitro IC50: 0.009 mM in fluorometric assay |
676812 |
1.1.1.213 | 0.05 |
- |
celecoxib |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.050 mM in fluorometric assay, in vitro IC50: 0.050 mM in fluorometric assay |
676812 |
1.1.1.213 | 0.0003 |
- |
2'-hydroxyflavanone |
- |
697265 |