EC Number   |
|---|
    1.2.1.12 | - |
| 1.2.1.12 | a high-resolution structure of 1.75 A is reported |
| 1.2.1.12 | after addition of NAD+ to the apoprotein |
| 1.2.1.12 | analysis of human GAPDH crystal structure, PDB ID 1U8F |
| 1.2.1.12 | crystalline enzyme does not contain NAD+ |
| 1.2.1.12 | crystallization of a a highly soluble form of GAPDS truncated at the N-terminus, amino acids 69398. The structure in complex with NAD+ and phosphate maps the two anion-recognition sites within the catalytic pocket that correspond to the conserved Ps site and Pi site identified in other organisms. The structure in complex with NAD+ and glycerol shows serendipitous binding of glycerol at the Ps and Pi sites |
| 1.2.1.12 | crystallization of the ternary complex between GAPDH, intrinsically disordered protein CP12 and NAD+ in both the absence and presence of copper. The oxidized CP12 proten becomes partially structured upon GAPDH binding. The C-terminus of CP12 is inserted into the active-site region of GAPDH, resulting in competitive inhibition of GAPDH |
| 1.2.1.12 | crystals of tag-free protein diffracts X-rays to 2.6 A resolution, of the His-tagged protein to 4.0 A |
| 1.2.1.12 | diffraction data to 2.3 A resolution are collected |
| 1.2.1.12 | enzyme carrying a fluorescent NAD+ derivative at 2.7 A resolution |
