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EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
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2.5.1.31
53
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the Tm of the UppS protein alone is 52.8 °C. In the presence of 0.01 mM inhibitor, the Tm shows a significant shift to higher temperature. The change in Tm is observed to be +8°C and +11°C with N-(3-amino-3-oxopropyl)-5-(benzo[b]thiophen-5-yl)-1-benzyl-N-(4-isopropoxybenzyl)-1H-pyrazole-4-carboxamide and N-(3-amino-3-oxopropyl)-1-benzyl-N-(4-isopropoxybenzyl)-5-(p-tolyl)-1H-pyrazole-4-carboxamide
759596
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