EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.1.11 | ATP + glutamate + putrescine |
the enzyme is involved in a putrescine utilization pathway |
Escherichia coli |
ADP + phosphate + gamma-L-glutamylputrescine |
- |
? |
6.3.1.11 | ATP + L-glutamate + putrescine |
- |
Escherichia coli |
ADP + phosphate + gamma-L-glutamylputrescine |
- |
? |
6.3.1.11 | ATP + L-glutamate + putrescine |
the enzyme catalyzes the gamma-glutamylation of putrescine, the first step in a different putrescine utilization pathway involving gamma-glutamylated intermediates, the Puu pathway, in Escherichia coli, overview. The intracellular concentration of putrescine is probably optimized by PuuA transcriptionally and posttranslationally and excess putrescine is converted to a nutrient source by the Puu pathway, regulation, overview |
Escherichia coli K-12 |
ADP + phosphate + gamma-L-glutamylputrescine |
- |
? |
6.3.1.11 | ATP + L-glutamate + putrescine |
PuuA exhibits the highest activity for putrescine, which has four carbon atoms, and activity drops when the methylene chain of diamine is longer or shorter than C4 |
Escherichia coli K-12 |
ADP + phosphate + gamma-L-glutamylputrescine |
- |
? |
6.3.1.11 | more |
intracellular polyamine profile of various strains relevant to puuA, overview |
Escherichia coli K-12 |
? |
- |
? |
6.3.1.11 | more |
when any one of the substrates and a cofactor , i.e. putrescine, glutamate, ATP, and the metal ion, are omitted from the reaction mixture, gamma-Glu-Put is not formed |
Escherichia coli K-12 |
? |
- |
? |