EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
    6.2.1.12 | ATP + 4-coumarate + CoA |
52% of the activity with caffeate |
Acetobacterium woodii |
AMP + diphosphate + 4-coumaroyl-CoA |
- |
? |
| 6.2.1.12 | ATP + caffeate + CoA |
- |
Acetobacterium woodii |
AMP + diphosphate + caffeoyl-CoA |
- |
? |
| 6.2.1.12 | ATP + caffeate + CoA |
the enzyme is involved in the reduction of the carbon-carbon double bond of phenylacrylates such as caffeate. The overall reaction is coupled to ATP synthesis by a chemiosmotic mechanism with Na+ as the coupling ion |
Acetobacterium woodii |
AMP + diphosphate + caffeoyl-CoA |
- |
? |
| 6.2.1.12 | ATP + cinnamate + CoA |
9% of the activity with caffeate |
Acetobacterium woodii |
AMP + diphosphate + cinnamoyl-CoA |
- |
? |
| 6.2.1.12 | ATP + ferulate + CoA |
16% of the activity with caffeate |
Acetobacterium woodii |
AMP + diphosphate + feruloyl-CoA |
- |
? |
| 6.2.1.12 | more |
no activity with either sinapate or 4-hydroxybenzoate. The more hydroxyl groups are present, the better is the activity of the enzyme. Methoxy groups on the aromatic ring have a negative effect on enzyme activity. It is possible that methoxy groups cause a steric obstruction. No activity can be measured if there is no acryl group present in the substrate |
Acetobacterium woodii |
? |
- |
? |
| 6.2.1.12 | ATP + 4-coumarate + CoA |
- |
Angelica sinensis |
AMP + diphosphate + 4-coumaroyl-CoA |
- |
? |
| 6.2.1.12 | 4-coumarate + MgATP2- + tetrapolyphosphate |
CoA omitted from the incubation mixture |
Arabidopsis thaliana |
adenosine 5'-pentaphosphate + ? |
- |
r |
| 6.2.1.12 | 4-coumarate + MgATP2- + tripolyphosphate |
CoA omitted from the incubation mixture |
Arabidopsis thaliana |
adenosine 5'-tetraphosphate + ? |
- |
r |
| 6.2.1.12 | AMP + 3-oxo-2-(2'-[Z]-pentenyl)-cyclopentane-1-butanoic acid + CoA |
weak substrate |
Arabidopsis thaliana |
? |
- |
? |
