EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.2.3.56 | (2E,6E)-farnesyl diphosphate |
- |
Abies grandis |
gamma-humulene + diphosphate |
gamma-humulene is the main product (30.9% yield) of the wild type enzyme |
? |
4.2.3.56 | (2E,6E)-farnesyl diphosphate |
- |
Abies grandis |
gamma-humulene + diphosphate |
main product with 28.6% yield |
? |
4.2.3.56 | more |
besides gamma-humulene (30.9% yield), gamma-humulene synthase produces 18.9% siberene, 11.4% longifolene, 7.4% beta-bisabolene, 4.3% sativene, 4.1% alpha-longipinene, 3.0% beta-farnesene, 2.6% alpha-ylangene, 2.1% beta-gurjunene, 2.0% gamma-bisabolene, 1.7% beta-longipinene, 1.3% alpha-bisaolene, 1.3% alpha-himachalene, 1.1% gamma-himachalene, 1.0% cyclosativene, 0.6% beta-ylangene, and 0.2% beta-cubebene |
Abies grandis |
? |
- |
? |
4.2.3.56 | more |
gamma-humulene synthase produces mainly gamma-humulene (28.6% yield) from (2E,6E)-farnesyl diphosphate, further products are sibirene (15.1% yield), longifolene (11.8% yield), beta-himachalene (7.2% yield), alpha-himachalene (4.8% yield), beta-bisabolene (3.9% yield), alpha-longipinene (3.4% yield), sativene (3.1% yield), alpha-ylangene (2.7% yield), beta-gurjunene (2.0% yield), gamma-bisabolene (1.9% yield), beta-longipinene (1.5% yield), (E)-beta-farnesene (1.3% yield), (E)-alpha-bisabolene (0.9% yield), delta-amorphene and alpha-amorphene (0.5% yield each), beta-ylangene (0.3% yield), 1,5,9-trimethylcyclododeca-1,5,9-triene and longicyclene (0.2% yield each), as well as beta-cubebene, alpha-copaene, alpha-cubebene, (Z,E)-germacrene B, and cyclosativene (0.1% yield each), along with 26 unknown sesquiterpene olefins (4.1% total yield) |
Abies grandis |
? |
- |
? |