EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.2.2.17 | DNA + H2O |
- |
Micrococcus luteus |
thymine + ? |
- |
? |
3.2.2.17 | DNA + H2O |
- |
Tequatrovirus T4 |
thymine + ? |
- |
? |
3.2.2.17 | DNA + H2O |
- |
Paramecium bursaria Chlorella virus 1 |
thymine + ? |
- |
? |
3.2.2.17 | DNA + H2O |
- |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | oligonucleotides + H2O |
- |
Micrococcus luteus |
dCMP + dTMP |
- |
? |
3.2.2.17 | poly(dAdT) + H2O |
- |
Tequatrovirus T4 |
oligonucleotides |
acid-soluble oligonucleotides, length less than 15 nucleotides |
? |
3.2.2.17 | more |
3'nicking is not result of the hydrolysis of the phospho ester bond, but rather result of a beta-elimination reaction, the sequence of the 138 amino acid residues of T4 UV endonuclease is known, active sites for DNA glycosylase and the nicking activity seem to be independent, since endonuclease is a phosphoric diester hydrolase classified as EC 3.1.4.-T4 UV endonuclease and Micrococcus luteus endonuclease are not endonucleases |
Micrococcus luteus |
? |
- |
? |
3.2.2.17 | more |
3'nicking is not result of the hydrolysis of the phospho ester bond, but rather result of a beta-elimination reaction, the sequence of the 138 amino acid residues of T4 UV endonuclease is known, active sites for DNA glycosylase and the nicking activity seem to be independent, since endonuclease is a phosphoric diester hydrolase classified as EC 3.1.4.-T4 UV endonuclease and Micrococcus luteus endonuclease are not endonucleases |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | oligonucleotide + H2O |
49-mers containing a single site-specific cis-syn, trans-syn I or trans-syn II thymine dimer |
Lysinibacillus sphaericus |
? |
beta elimination reaction results in products wich have 3'4-hydroxy-2-pentanal ends |
? |
3.2.2.17 | oligonucleotide + H2O |
49-mers radiolabeled containing a site-specific uracil with uracil DNA glycosylase |
Lysinibacillus sphaericus |
? |
incise of AP sites resulting in beta- and delta-elimination products with 3'4-hydroxy-2-pentenal and 3'-phosphate termini respectively |
? |