EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.8.15 | more |
alg7 mutants show diminished activity of GPT, reduced steady-state levels of lipid-linked oligosaccharides and hypoglycosylated carboxypeptidase Y. Mutants also lack mitochondrial DNA including the genes that encode the components of the respiratory machinery |
Saccharomyces cerevisiae |
? |
- |
? |
2.7.8.15 | more |
overexpression of GPT in CHO-K1 cells does not go along with accumulation of intermediate Man5GlcNAc2-diphosphodolichol because of alteration of levels of oligosaccharide-diphosphodolichol and monosaccharide-phosphodolichol or through GPT enzymatic activity and excessive dolichyl phosphate consumption but rather may interfere with utilization of mannose- and glucosephosphodolichol |
Cricetulus griseus |
? |
- |
? |
2.7.8.15 | more |
the uridine moiety of UDP-GlcNAc is coordinated with eight hydrogen bonds between the one backbone amide (Leu46), seven side chains of the amino acids and two water molecules. The uridine moiety of tunicamycin occupies the identical binding sites of UDP-GlcNAc |
Homo sapiens |
? |
- |
- |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Cricetulus griseus |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Mus musculus |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Homo sapiens |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Rattus norvegicus |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Sus scrofa |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Sus scrofa |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
r |
2.7.8.15 | UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate |
- |
Saccharomyces cerevisiae |
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol |
- |
? |