EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.104 | more |
caffeoyl-CoA preferred to 5-hydroxyferuoyl-CoA |
Nicotiana tabacum |
? |
- |
? |
2.1.1.104 | more |
caffeoyl-CoA preferred to 5-hydroxyferuoyl-CoA |
Vitis vinifera |
? |
- |
? |
2.1.1.104 | more |
no substrates are caffeic acid, bergaptol, xanthotoxol, luteolin, esculetin |
Petroselinum crispum |
? |
- |
? |
2.1.1.104 | more |
CCoAOMT down-regulation induces changes in xylem cell-wall structure and the lignin fractions |
Linum usitatissimum |
? |
- |
? |
2.1.1.104 | more |
COMT catalyzes the multi-step methylation reactions of hydroxylated monomeric lignin precursors, and plays a pivotal position in the lignin biosynthetic pathway |
Triticum aestivum |
? |
- |
? |
2.1.1.104 | more |
COMT catalyzes the multi-step methylation reactions of hydroxylated monomeric lignin precursors, and plays a pivotal position in the lignin biosynthetic pathway |
Nicotiana tabacum |
? |
- |
? |
2.1.1.104 | more |
CoA and caffeoyl CoA are binding with high affinity to the enzymes in the presence and absence of S-adenosyl-L-methionine, thereby with higher affinity to isozyme CCoAOMT2 than CCoAOMT1, molecular dynamics, simulations, and docking analysis, overview. Conserved active site residues Met58, Thr60, Val63, Glu82, Gly84, Ser90, Asp160, Asp162, Thr169, Asn191 and Arg203 in CCoAOMT1 and CCoAOMT2 enzymes create the positive charge to balance the negatively charged caffeoyl CoA and play an important role in maintaining a functional conformation and are directly involved in donor substrate binding |
Leucaena leucocephala |
? |
- |
? |
2.1.1.104 | more |
flax CCoAOMT possesses a small, but probably significant 5' methylating activity, in addition to a more usual 3' methylating activity |
Linum usitatissimum |
? |
- |
? |
2.1.1.104 | more |
OMT-15 and -17 cannot utilize naringenin, apigenin, or kaempferol as substrates, taxifolin and eriodictyol do not serve as methyl acceptors |
Oryza sativa |
? |
- |
? |
2.1.1.104 | more |
the enzyme is capable of 3'- and 5'-methylating not only acid, aldehyde and alcohol precursors, but also ester precursors, broad substrate specificity, overview |
Triticum aestivum |
? |
- |
? |