EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.21 | 3-demethylfarnesyl diphosphate + NADPH |
- |
Rattus norvegicus |
10-demethylsqualene + NADP+ + diphosphate |
- |
? |
2.5.1.21 | 3-demethylfarnesyl diphosphate + NADPH |
- |
Saccharomyces cerevisiae |
10-demethylsqualene + NADP+ + diphosphate |
- |
? |
2.5.1.21 | 2-methylfarnesyl diphosphate + NADPH |
- |
Rattus norvegicus |
11-methylsqualene + NADP+ + diphosphate |
- |
? |
2.5.1.21 | 2-methylfarnesyl diphosphate + NADPH |
- |
Saccharomyces cerevisiae |
11-methylsqualene + NADP+ + diphosphate |
- |
? |
2.5.1.21 | farnesyl diphosphate |
- |
Sus scrofa |
12,13-cis-dehydrosqualene + diphosphate |
- |
? |
2.5.1.21 | farnesyl diphosphate |
- |
Saccharomyces cerevisiae |
12,13-cis-dehydrosqualene + diphosphate |
- |
? |
2.5.1.21 | farnesyl diphosphate |
in presence of Mn2+ |
Saccharomyces cerevisiae |
12,13-cis-dehydrosqualene + diphosphate |
12-cis-dehydrosqualene + diphosphate |
? |
2.5.1.21 | 10,11-dihydrofarnesyl diphosphate + NADPH |
at 60% of the efficiency that farnesyl diphosphate is converted to squalene |
Saccharomyces cerevisiae |
2,3,22,23-tetrahydrosqualene + NADP+ + diphosphate |
- |
? |
2.5.1.21 | (E,E)-7-desmethylfarnesyl diphosphate + NADPH |
at 60% of the efficiency that farnesyl diphosphate is converted to squalene |
Saccharomyces cerevisiae |
6,19-didesmethylsqualene + NADP+ + diphosphate |
in absence of farnesyl diphosphate, 6-desmethylsqualene is produced in presence of farnesyl diphosphate |
? |
2.5.1.21 | more |
specificity overview |
Rattus norvegicus |
? |
- |
? |