EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.2.2.17 | DNA + H2O |
- |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | DNA + H2O |
UV-irradiated DNA, containing thymine dimers |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | DNA + H2O |
pyrimidine cyclobutane dimer formed between adjacent pyrimidines |
Micrococcus luteus |
? |
- |
? |
3.2.2.17 | DNA + H2O |
removal of UV-induced pyrimidine dimer photoproducts |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | DNA + H2O |
the combined rate of sugar ring opening and reduction of the sugar is significantly slower than the rate of formation of (T4-pdg)-DNA intermediate |
Escherichia coli |
? |
- |
? |
3.2.2.17 | DNA + H2O |
the enzyme incises DNA at cyclobutane pyrimidine dimers that are formed as a consequence of exposure to ultraviolet light. The investigation reveals a temporal uncoupling of the T4-Pdg-induced DNA bending and nucleotide flipping |
Tequatrovirus T4 |
? |
- |
? |
3.2.2.17 | DNA phiX174 RFI + H2O |
irradiated with increasing doses of UV light |
Micrococcus luteus |
thymine + ? |
- |
? |
3.2.2.17 | DNA phiX174 RFI + H2O |
double-stranded covalently closed circular DNA molecule contains apurinic sites |
Micrococcus luteus |
thymine + ? |
- |
? |
3.2.2.17 | more |
3'nicking is not result of the hydrolysis of the phospho ester bond, but rather result of a beta-elimination reaction, the sequence of the 138 amino acid residues of T4 UV endonuclease is known, active sites for DNA glycosylase and the nicking activity seem to be independent, since endonuclease is a phosphoric diester hydrolase classified as EC 3.1.4.-T4 UV endonuclease and Micrococcus luteus endonuclease are not endonucleases |
Micrococcus luteus |
? |
- |
? |
3.2.2.17 | more |
3'nicking is not result of the hydrolysis of the phospho ester bond, but rather result of a beta-elimination reaction, the sequence of the 138 amino acid residues of T4 UV endonuclease is known, active sites for DNA glycosylase and the nicking activity seem to be independent, since endonuclease is a phosphoric diester hydrolase classified as EC 3.1.4.-T4 UV endonuclease and Micrococcus luteus endonuclease are not endonucleases |
Tequatrovirus T4 |
? |
- |
? |