EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.1.6 | more |
mechanism of the reaction is sequential in both directions. Residue Asp183 acts as a catalytic base that deprotonates the C1 hydroxyl group of galactose. The pH-kcat profile of the synthesis of galactose 1-phosphate has a pKa of 6.9 likely due to Asp183. The pH-kcat/KGal profile of the reverse reaction lacks a key pKa required for a direct proton transfer mechanism. Arg36 may lower the pKa of the C1 hydroxyl to facilitate deprotonation |
Lactococcus lactis |
? |
- |
? |
2.7.1.6 | more |
L-arabinose, D-fucose, L-glucose, and D-talose are no substrates |
Saccharomyces cerevisiae mc2 |
? |
- |
? |
2.7.1.6 | more |
induction of the gal pathway and cellulase genes involves no transcriptional inducer function of the galactokinase in Hypocrea jecorina |
Trichoderma reesei QM9414 |
? |
- |
? |
2.7.1.6 | UTP + D-galactose |
substrate: UTP, specific activity: 0.52 micromol/min/mg |
Bifidobacterium longum subsp. infantis |
UDP + alpha-D-galactose 1-phosphate |
- |
? |