EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.73 | O-phospho-L-seryl-tRNACys + sulfide |
all three highly conserved Cys residues in the enzyme (Cys64, Cys67, and Cys272) are essential for the sulfhydrylation reaction in vivo. Cys64 and Cys67 form a disulfide linkage and carry a sulfane sulfur in a portion of the enzyme. A persulfide group (containing a sulfane sulfur) is the proximal sulfur donor for cysteine biosynthesis |
Methanocaldococcus jannaschii DSM 2661 |
L-cysteinyl-tRNACys + phosphate |
- |
? |
2.5.1.73 | O-phospho-L-seryl-tRNASec + sulfide |
selenocysteinyl-specific O-phospho-L-seryl-tRNASec is recognized as a substrate, presence of the O-phospho-L-seryl moiety is crucial for recognition |
Escherichia coli |
L-cysteinyl-tRNASec + phosphate |
- |
? |