EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.126 | beta-amyrin + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 |
overall reaction |
Ocimum basilicum |
oleanolate + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O |
- |
? |
1.14.14.126 | beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 |
overall reaction |
Medicago truncatula |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
CYP716A12 mainly catalyzes the sequential three-step oxidation at the C-28 position necessary to transform beta-amyrin into oleanolic acid |
? |
1.14.14.126 | germanicol + 3 O2 + 3 NADPH + 3 H+ |
overall reaction |
Malus domestica |
morolate + 3 NADP+ + 4 H2O |
- |
? |
1.14.14.126 | lupeol + 3 O2 + 3 NADPH + 3 H+ |
overall reaction |
Malus domestica |
betulinate + 3 NADP+ + 4 H2O |
- |
? |
1.14.14.126 | lupeol + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 |
overall reaction |
Glycyrrhiza uralensis |
betulinic acid + 3 [oxidized NADPH-hemoprotein reductase] + 4 H2O |
- |
? |
1.14.14.126 | beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 |
production of oleanolate in grape skin |
Vitis vinifera |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | more |
the enzyme catalyzes a three-step oxidation reaction at the C-28 position of beta-amyrin, alpha-amyrin, and lupeol to produce oleanolic acid, ursolic acid, and betulinic acid, respectively |
Glycyrrhiza uralensis |
? |
- |
? |
1.14.14.126 | more |
the enzyme catalyzes a three-step oxidation reaction at the C-28 position of beta-amyrin, alpha-amyrin, and lupeol to produce oleanolic acid, ursolic acid, and betulinic acid, respectively |
Glycyrrhiza uralensis 308-19 |
? |
- |
? |
1.14.14.126 | beta-amyrin + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro |
Panax ginseng |
oleanolate + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.126 | more |
the enzyme produces erythrodiol and oleanolic acid as C-28 oxidation products of beta-amyrin |
Solanum lycopersicum |
? |
- |
? |