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Search term: placental cell line

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EC Number	Recommended Name	Source Tissue	Commentary	Reference
3.4.24.86	ADAM 17 endopeptidase	placental cell line	Villous explant cultures or cytotrophoblastic cells are used. Preadministration of TACE inhibitor in villous explant cultures or transfection of cytotrophoblastic cells with TACE-specific small interference RNA decreases the shedding of heparin-binding epidermal growth factor-like growth factor and amphiregulin. Hypoxia (2% O2) causes an increase in the levels of TACE mRNA and protein in villous explants and primary cytotrophoblastic cells in vitro	701164

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Release 2023.1 (January 2023)