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EC Number
Source Tissue
Commentary
Reference
3.4.14.1
culture fluid
secretion of active enzyme is stimulated by thyrotropin, insulin, and/or somatostatin
731377
3.4.14.1
culture medium
very low cathepsin C activity in culture medium of untreated keratinocytes, suggesting that the constitutive exocytosis of lysosomes is weak in keratinocytes. Treatment with 0.03 mM ionomycin for 50 min induces the release of about 20% of cathepsin C activity. Incubation of keratinocytes for 30 min with 1 mM calcium and 0.01 mM ionomycin causes a significant release of cathepsin C activity
663783
3.4.14.1
cytotoxic T-cell
high activity
36150
3.4.14.1
dendritic cell
cathepsin C activity in monocyte derived dendritic cells (ex vivo) decreases dramatically as they mature
665144
3.4.14.1
enamel organ
-
693377
3.4.14.1
esophageal adenocarcinoma cell
gene for cathepsin C is upregulated compared to Barrett's esophagus
667004
3.4.14.1
esophageal mucosa
-
667005
3.4.14.1
esophageal squamous cell carcinoma cell
activity of dipeptidyl-peptidase I increases significantly as compared to the normal esophageal mucosa
667005
3.4.14.1
esophagus
epithelium from normal control Barrett's esophagus
667004
3.4.14.1
FRTL-5 cell
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731377
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