EC Number   |
General Information |
Reference |
|---|
  2.1.1.382 | metabolism |
oxygen-independent demethylation via methyl transfer is mediated by cobalamin-dependent veratrol-O-demethylase VdmB |
763782 |
| 2.1.1.382 | physiological function |
a most upregulated gene clusters under methoxydotrophic growth contains genes encoding the O-demethylase MtoB, is responsible for O-demethylation of the methoxy compound, the cobalamin binding protein MtoC that accepts the methyl group from MtoB, the reductive activase of MtoC named MtoD, the methyl transferase MtoA which most likely transfers the methyl group from MtoC to tetrahydomethanopterin (H4MPT), and major facilitator superfamily transporters |
764583 |
| 2.1.1.382 | physiological function |
an ether-cleaving O-demethylase isolated from syringate-grown cells consists of four proteins, components A, B, C and D. The enzyme system converts only phenyl methyl ethers with a hydroxyl group in the ortho position to the methoxyl moiety. The presence of a carboxyl group in the aromatic compound is not required. Component B serves as vanillate:corrinoid protein methyltransferase (methyltransferase I) mediating the methyl transfer from vanillate to the reduced corrinoid protein component A |
764616 |
| 2.1.1.382 | physiological function |
Moorella thermoacetica encodes several homologs of MtvA, MtvB and MtvC genes possibly used for growth on methyl donors other than vanillate and methanol. The function of MtvB is clearly associated with methyl transfer |
764579 |
| 2.1.1.382 | physiological function |
MtvB is part of an inducible three-component aromatic O-demethylase system. MtvB catalyzes methyl transfer from a phenylmethylether to the cobalt center of MtvC, a corrinoid protein. All three protein components are required for O-demethylase activity |
764996 |
| 2.1.1.382 | physiological function |
under methoxydotrophic growth, Methermicoccus shengliensis expresses an O-demethylation/methyltransferase system related to the one used by acetogenic bacteria. The methyl group is transferred from the methoxy compound via a two step-mechanism, first transfer on cobalamin and then further transfer on the C1-carrier tetrahydromethanopterin |
764942 |
