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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11evolution N-demethylase enzymes (NND) belongs to the family of cytochrome P450 monooxygenases (CYP). The CYP82E21 gene is found in all Nicotiana tabacum cultivars analysed and originates from the tobacco ancestor Nicotiana tomentosiformis 746003
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11malfunction nornicotine formation can be reduced in ovaries by introducing a CYP82E21-specific RNAi construct 746003
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11malfunction RNA interference of the nicotine demethylase gene CYP82E4v1 reduces nornicotine content and enhances Myzus persicae resistance in Nicotiana tabacum infected with aphids 746124
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11physiological function only microsomes from yeast expressing the D121-AA8 cDNA exhibit significant nicotine demethylase activity 700634
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.B11physiological function the CYP82E21 gene encodes a functional ovary-specific nicotine N-demethylase, nornicotine is formed by oxidative demethylation of nicotine 746003
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