EC Number   |
General Information |
Reference |
|---|
   1.14.11.67 | evolution |
5 isozymes of enzyme Jarid/KDM5 (Jarid1A-D and Jarid2) in Caenorhabditis elegans, overview |
753349 |
| 1.14.11.67 | evolution |
5 isozymes of enzyme Jarid/KDM5 (Jarid1A-D and Jarid2) in Drosophila melanogaster, overview |
753349 |
| 1.14.11.67 | evolution |
Fbxl10 (Jhdm1b/Kdm2b) is a conserved and ubiquitously expressed member of the JHDM (JmjC domain-containing histone demethylase) family |
725484 |
| 1.14.11.67 | evolution |
Jhd2 belongs to an expansive protein family distinguished by the presence of a JmjC domain. The JmjC domain, initially identified in the C-terminal region of the mouse Jumonji protein, mediates the demethylation of histone lysine residues |
746464 |
| 1.14.11.67 | evolution |
Jhd2 is an evolutionarily conserved JARID1 family H3 Lys4 demethylase and a Jumonji C (JmjC) domain-containing histone demethylase (JHDM). Jhd2/Kdm5 is an evolutionarily conserved JARID1 family protein that has demethylase activity toward H3K4me3 in vitro or in vivo |
744589 |
| 1.14.11.67 | evolution |
JMJ703 is the homolog of the Arabidopsis thaliana H3K4 demethylase JMJ14, which is involved in flowering time regulation and gene silencing |
755243 |
| 1.14.11.67 | evolution |
KDM5C is a member of the evolutionarily conserved KDM5 family of four proteins, KDM5A/B/C and D. KDM5A/C/D demethylate tri- and di-methylated forms of H3K4, whereas KDM5B is capable of demethylating all three forms (tri-, di-, and mono) of H3K4 methylation |
724667 |
| 1.14.11.67 | evolution |
RBR-2 is the sole homolog of the KDM5 family of H3K4me3/2 demethylases in Caenorhabditis elegans |
744762 |
| 1.14.11.67 | evolution |
the enzyme belongs to the JARID family. JARID proteins contain, in addition to the JmjN and JmjC domains, ARID and C5HC2-zinc finger domains, which mediate DNA binding. JARID proteins are, in turn, divided into two subgroups according to the presence, JARID1, or not, JARID2, of chromatin-binding PHD domains. CG3654 is the structural homologue of mammalian JARID2, as it does not contain any chromatin-binding domains. In this case, however, identity is lower (15%) and, in addition, CG3654 is missing the C5HC2-zinc finger domain present in mammalian JARID2 |
754921 |
| 1.14.11.67 | evolution |
the enzyme belongs to the superfamily of flavin adenine dinucleotide (FAD)-dependent amine oxidases |
744188 |
