EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
2.4.2.29 | 758889 |
Crystal structure of the human tRNA guanine transglycosylase catalytic subunit QTRT1 |
Biomolecules |
8 |
81 |
2018 |
Homo sapiens |
30149595 |
2.4.2.29 | 705164 |
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction |
J. Mol. Biol. |
393 |
833-847 |
2009 |
Zymomonas mobilis |
19627989 |
2.4.2.29 | 703202 |
Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT |
ChemBioChem |
10 |
716-727 |
2009 |
Zymomonas mobilis |
19199329 |
2.4.2.29 | 644930 |
Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange |
EMBO J. |
15 |
2850-2857 |
1996 |
Zymomonas mobilis |
8654383 |
2.4.2.29 | 681439 |
Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding |
J. Mol. Biol. |
370 |
492-511 |
2007 |
Zymomonas mobilis |
17524419 |
2.4.2.29 | 658379 |
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer |
Cancer Lett. |
212 |
113-119 |
2004 |
Homo sapiens |
15246567 |
2.4.2.29 | 722058 |
From lin-benzoguanines to lin-benzohypoxanthines as ligands for Zymomonas mobilis tRNA-guanine transglycosylase: replacement of protein-ligand hydrogen bonding by importing water clusters |
Chemistry |
18 |
9246-9257 |
2012 |
Zymomonas mobilis |
22736391 |
2.4.2.29 | 688390 |
Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies |
J. Mol. Biol. |
374 |
764-776 |
2007 |
Zymomonas mobilis |
17949745 |
2.4.2.29 | 703213 |
High-affinity inhibitors of tRNA-guanine transglycosylase replacing the function of a structural water cluster |
Chemistry |
15 |
10809-10817 |
2009 |
Zymomonas mobilis |
19746363 |
2.4.2.29 | 703226 |
How to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylase |
ChemMedChem |
4 |
2012-2023 |
2009 |
Zymomonas mobilis |
19894214 |