EC Number |
Posttranslational Modification |
Reference |
---|
3.4.16.5 | glycoprotein |
- |
-, 647222, 647226, 665664, 677947 |
3.4.16.5 | glycoprotein |
11% carbohydrate, isoenzyme MpiCP-1 |
665932 |
3.4.16.5 | glycoprotein |
16 residues of glucosamine and about 15% hexose |
647189, 647195 |
3.4.16.5 | glycoprotein |
25.3% carbohydrate, mannose 83.3% by weight, glucosamine 10.3%, with traces of galactose and galactosamine |
647206 |
3.4.16.5 | glycoprotein |
33% carbohydrate, isoenzyme MpiCP-2 |
665932 |
3.4.16.5 | glycoprotein |
contains 17% carbohydrate |
665930 |
3.4.16.5 | glycoprotein |
CPY shows microheterogeneity in N-glycans such as Man11-15GlcNAc2 at Asn13, Man8-12GlcNAc2 at Asn87, Man9-14GlcNAc2 at Asn168 and phosphorylated Man12-17GlcNAc2 as well as Man11-16GlcNAc2 at Asn368. In vacuoles the steady release of mannose/phosphomannose residues from glycans may occur initially at Asn13 or Asn168 followed by at Asn368 |
753875 |
3.4.16.5 | glycoprotein |
structural integrity and functional activity is influenced by its associated carbohydrate component |
647207 |
3.4.16.5 | glycoprotein |
the carbohydrate moiety has a slightly protective role in heat-induced unfolding and highly protective role the enzyme against pressure induced denaturation |
647229 |
3.4.16.5 | glycoprotein |
the enzyme is synthesized as a prepro-form that travels through the endoplasmic reticulum and Golgi to its final destination in vacuoles. Various post-translational events have been identified, e.g. carbohydrate modification and cleavage of the presegments. Core glycosylation occurs to a 67000 Da form called p1-CPY. Oligosaccharide modification is completed to give p2-CPY, 69000 Da, in which 2 N-acetyl-glucosamines and 8-14 mannoses, including a 1 mannosyl-phosphate group are attached |
647224 |