EC Number   |
Natural Substrates |
|---|
    6.1.1.17 | ATP + L-glutamate + tRNAGln |
- |
| 6.1.1.17 | ATP + L-glutamate + tRNAGlu |
- |
| 6.1.1.17 | ATP + L-glutamate + tRNAGln |
enzyme expressed in an Escherichia coli mutant strain, tRNAGln UUG from Escherichia coli |
| 6.1.1.17 | ATP + L-glutamate + tRNAGlu |
eukaryotic-type discriminating glutamyl-tRNA synthetase, inability to utilize Escherichia coli tRNA as substrate. The enzyme is essential for growth of insect stage Trypanosoma brucei and is responsible for essentially all of the glutamyl-tRNA synthetase activity in cytosol and in mitochondria |
| 6.1.1.17 | more |
GluRS plays a major role in regulating the cellular level of heme, aminoacylation of tRNAGlu correlates with the demand of heme, a transcriptional mechanism might control the level of GluRS1 in cells grown in Fe2+, under growth conditions in which cells do not require Glu-tRNA, as precursor for heme biosynthesis, up to 85% of GluRS1 is dispensable, but no major detrimental effect in the cell growth is observed. Thus, GluRS2 and the remaining 15% of the activity of GluRS1 are sufficient to provide the Glu-tRNA substrates for protein synthesis |
| 6.1.1.17 | ATP + L-glutamate + tRNAGlu |
glutamyl-tRNA, formed by Glu-tRNA synthetase, is a substrate for protein biosynthesis and tetrapyrrole formation by the C5 pathway |
| 6.1.1.17 | more |
GtS is an age-dependent Streptococcus pneumoniae antigen and is a surface-located adhesin that is capable of inducing a partially protective immune response against Streptococcus pneumoniae in mice, overview |
| 6.1.1.17 | ATP + L-glutamate + tRNAGlu |
involved in synthesis of 5-aminolevulinate (a committed and regulated precursor in the chlorophyll biosynthetic pathway) |
| 6.1.1.17 | ATP + L-glutamate + tRNAGlu |
isozyme 1 expressed in an Escherichia coli mutant strain, tRNAGlu from Escherichia coli |
| 6.1.1.17 | ATP + L-glutamate + tRNAGln |
isozyme 2 expressed in an Escherichia coli mutant strain, tRNAGln UUG from Escherichia coli |
