EC Number   |
Natural Substrates |
|---|
    4.3.2.1 | (Nomega-L-arginino)succinate |
- |
| 4.3.2.1 | (Nomega-L-arginino)succinate |
last step in the biosynthesis of arginine |
| 4.3.2.1 | 2-(Nomega-L-arginino)succinate |
- |
| 4.3.2.1 | 2-(Nomega-L-arginino)succinate |
as part of the urea cycle, the enzyme is essential for ammonia detoxification and L-arginine synthesis |
| 4.3.2.1 | 2-(Nomega-L-arginino)succinate |
last enzyme of the arginine biosynthesis pathway |
| 4.3.2.1 | argininosuccinate |
- |
| 4.3.2.1 | argininosuccinate |
biological activity in liver, ileum, small intestine, heart, lung and kidney within the urea and nitric oxide cycle |
| 4.3.2.1 | argininosuccinate |
urea cycle enzyme, deficiency results in argininosuccinic aciduria |
| 4.3.2.1 | fumarate + L-arginine |
accumulation of fumarate leads to reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells |
| 4.3.2.1 | more |
metabolic role in biosynthesis of Arg and urea |
