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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the reaction diagram Show all sequences 3.5.1.B134-deoxy-4-formamido-beta-L-arabinopyranosyl undecaprenyl phosphate + H2O because the L-Ara4N unit attached to lipid A is not derivatized with a formyl group, the existence of a deformylase, acting later in the pathway, is postulated. The requirement of the ArnA formyltransferase reaction for the maintenance of polymyxin resistance suggests that an as yet unidentified deformylase must also exist, since neither L-Ara4N-modified lipid A nor the L-Ara4N donor, undecaprenyl phosphate-L-Ara4N, is formylated when isolated from polymyxin resistant cells
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