EC Number |
Natural Substrates |
---|
3.1.30.2 | DNA + H2O |
- |
3.1.30.2 | DNA + H2O |
dsDNA to ssDNA preference ratio for Par_DSN-t4 is equal to 10, corresponding ratio for intact Par_DSN is equal to 1000 |
3.1.30.2 | DNA + H2O |
protein and DNA are held together by a mix of salt-bridges, water-mediated and direct hydrogen bond interactions between the protein and DNA backbone, almost no DNA bases are directly involved in the contacts |
3.1.30.2 | dsDNA + H2O |
- |
3.1.30.2 | dsDNA + H2O |
hydrolysis of nucleic acids |
3.1.30.2 | dsDNA + H2O |
physiological function currently unknown |
3.1.30.2 | dsDNA + H2O |
primarily responsible for internucleosomal DNA cleavage during the terminal stages of apoptosis, preference for cleaving the internucleosomal linker regions in chromatin |
3.1.30.2 | flap DNA + H2O |
- |
3.1.30.2 | more |
substrate specificity in descending order is ssDNA, dsDNA, RNA |
3.1.30.2 | more |
recombinant protein is active on plasmid DNA, circular recessed and flap M13 substrate with short protruding single strand |