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Results 1 - 10 of 16

EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.8.3.5	succinyl-CoA + 3-hydroxybutyrate	-
2.8.3.5	succinyl-CoA + a 3-oxo acid	-
2.8.3.5	succinyl-CoA + acetoacetate	-
2.8.3.5	succinyl-CoA + beta-hydroxybutyrate	-
2.8.3.5	succinyl-CoA + acetoacetate	enzyme deficiency leads to ketoacidotic crises and persistent ketosis
2.8.3.5	succinyl-CoA + beta-hydroxybutyrate	essential enzyme in the metabolism of ketone bodies in higher animals
2.8.3.5	succinyl-CoA + acetoacetate	essential enzyme in the metabolism of ketone bodies in higher animals, reaction via an enzyme-thioester intermediate
2.8.3.5	succinyl-CoA + acetoacetate	involved in the breakdown of ketone bodies in the extrahepatic tissues, mainly heart and skeletal muscle, SCOT catalyzes the conversion of the main ketone body, acetoacetate, into acetoacetyl-CoA, which is subsequently metabolized via citric acid cycle for energy production
2.8.3.5	succinyl-CoA + acetoacetate	ketolytic enzyme, uniquely involved in complete oxidation of ketone bodies
2.8.3.5	succinyl-CoA + a 3-oxo acid	ketone bodies, produced mainly in the liver, are an important source of energy for extrahepatic tissues

Results 1 - 10 of 16

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Release 2023.1 (January 2023)