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Results 1 - 3 of 3

EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.7.7.85	2 ATP	-
2.7.7.85	2 ATP	specific recognition of adenine in the active site pocked. The enzyme signals DNA structures that interfere with chromosome segregation cyclic di-3',5'-adenylate. The enzyme activity is unaffected by linear DNA or DNA ends but strongly suppressed by branched nucleic acids such as Holliday junctions
2.7.7.85	2 ATP	the intracellular bacterial pathogen Listeria monocytogenes secretes cyclic di-3',5'-adenylate into the cytosol of the host, where it triggers a cytosolic pathway of innate immunity

Results 1 - 3 of 3

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Release 2023.1 (January 2023)