EC Number |
Natural Substrates |
---|
2.5.1.46 | more |
deoxyhypusine synthase-suppressed Brassica napus plants have larger leaves as well as enhanced seed yield, this appears to reflect increased tolerance to chronic sublethal stress |
2.5.1.46 | more |
as racemic mixtures, only 2-MeSpd and 3-MeSpd support long-term growth (9-18 days) of spermidine-depleted DU-145 cells, whereas gamma-MeSpd and omega-MeSpd do not |
2.5.1.46 | more |
the rTvDHS enzyme is bifunctional and is also involved in the hydroxylation of deoxyhypusine-containing rTveIF-5A, cf. EC 1.14.99.29 |
2.5.1.46 | [eIF5A-precursor]-lysine + 2-methylspermidine |
- |
2.5.1.46 | [eIF5A-precursor]-lysine + 3-methylspermidine |
- |
2.5.1.46 | [eIF5A-precursor]-lysine + spermidine |
- |
2.5.1.46 | [eIF5A-precursor]-lysine + spermidine |
posttranslational activation of the initiation factor 5A |
2.5.1.46 | [eIF5A-precursor]-lysine + spermidine |
first step in the biosynthesis of hypusine |
2.5.1.46 | [eIF5A-precursor]-lysine + spermidine |
the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form |
2.5.1.46 | [eIF5A-precursor]-lysine + spermidine |
posttranslational activation of eIF-5A which has a specialized role in proliferation and in serum starvation-induced apoptosis in endothelial cells |