EC Number |
Natural Substrates |
---|
3.4.23.16 | eIF4GI + H2O |
perhaps cleavage of eIF4G is an event that contributes to a more efficient translation of the genomic HIV-1 mRNA, proteolysis of eIF4GI inhibits protein synthesis directed by capped mRNAs but allows internal ribosome entry site-driven translation, purified enzyme cleaves at positions 678-679, 681-682 and 1086-1087, separating the three domains of the initiation factor |
3.4.23.16 | Gag polyprotein + H2O |
- |
3.4.23.16 | Gag polyprotein + H2O |
substrate sites, overview |
3.4.23.16 | Gag polyprotein + H2O |
Gag polyprotein with cleavage-site P12-P5/P5'-P12' residues |
3.4.23.16 | Gag precursor polyprotein + H2O |
- |
3.4.23.16 | Gag protein + H2O |
proteolytic cleavage in the host cell cytoplasm |
3.4.23.16 | Gag-Pol polyprotein + H2O |
- |
3.4.23.16 | Gag-Pol polyprotein + H2O |
proteolytic cleavage in the host cell cytoplasm |
3.4.23.16 | Gag-Pol precursor polyprotein + H2O |
- |
3.4.23.16 | Gag-pro-pol polyprotein + H2O |
- |