EC Number   |
Natural Substrates |
|---|
   3.4.11.1 | His-Leu + H2O |
- |
| 3.4.11.1 | kallidin + H2O |
i.e. LRPPGFSPFR |
| 3.4.11.1 | L-Leu-7-amido-4-methylcoumarin + H2O |
- |
| 3.4.11.1 | Leu-Leu + H2O |
- |
| 3.4.11.1 | Met-Leu + H2O |
- |
| 3.4.11.1 | more |
- |
| 3.4.11.1 | more |
broad substrate specificity towards naturally occurring peptide hormones, while the enzyme hydrolyzes synthetic substrate in vitro with specificity for leucine, enzyme plays a role in regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney |
| 3.4.11.1 | more |
enzyme activity is regulated on the transcriptional level |
| 3.4.11.1 | more |
no growth on QL, FL, YL, WL, IL, VL, KL, GL, RL, and PL |
| 3.4.11.1 | more |
A-LAP plays a key role in the MHC class I antigen-presentation pathway, the enzyme is involved in the renin-angiotensin-system, RAS, and angiotensin II metabolism, and plays a role in blood pressure decrease through inactivation of angiotensin II, overview |
