EC Number |
Natural Substrates |
---|
3.1.3.46 | D-fructose 2,6-bisphosphate + H2O |
- |
3.1.3.46 | fructose 2,6-bisphosphate + H2O |
- |
3.1.3.46 | more |
enzyme involved in regulation of glycolytic flux, role of glycolysis in cell cycle progression |
3.1.3.46 | more |
enzyme expression is highly reduced in diabetic mice, insulin is required for enzyme induction/regulation, a high enzyme expression level reduces blood glucose level and increases the expression of glucokinase, metabolic regulation overview |
3.1.3.46 | more |
inducible isozyme PFKFB3 plays a crucial role in the progression of cancerous cells by enabling their glycolytic pathways, overview |
3.1.3.46 | more |
metabolic regulation, overview |
3.1.3.46 | more |
PFKFB3 overexpression increases the glycolysis level |
3.1.3.46 | more |
study of bifunctional enzyme evolution |
3.1.3.46 | more |
the enzyme is important in degradation of the biolocical factor beta-D-fructose 2,6-bisphosphate, the bifunctional PFK-2/FDPase-2 shows a metabolic switch to change between the two separate activities, involved in glycolysis and gluconeogenesis, metabolic regulation overview |
3.1.3.46 | more |
the enzyme is important in degradation of the biological factor beta-D-fructose 2,6-bisphosphate, the bifunctional PFK-2/FDPase-2 shows a metabolic switch to change between the two separate activities, metabolic regulation overview |