EC Number |
Natural Substrates |
---|
2.7.11.15 | ATP + beta-adrenergic receptor |
beta-ARK 1 might be involved in uncoupling and down-regulation of beta-AR, presumably both beta1- and beta2-AR, in failing hearts via receptor phosphorylation |
2.7.11.15 | ATP + beta-adrenergic receptor |
presumably modulates some receptor-mediated immune functions |
2.7.11.15 | ATP + beta-adrenergic receptor |
role of beta-ARK 1 in heart failure, myocardial development and function |
2.7.11.15 | ATP + beta-adrenergic receptor |
natural substrate: beta2-adrenergic receptor |
2.7.11.15 | ATP + beta-adrenergic receptor |
beta-ARK 1 and 2 may have a similar substrate specificity in vivo |
2.7.11.15 | ATP + beta-adrenergic receptor |
regulation of the beta-AR function in vivo |
2.7.11.15 | ATP + beta-adrenergic receptor |
desensitization of beta-adrenergic receptor |
2.7.11.15 | ATP + beta-adrenergic receptor |
plays, together with cAMP-dependent protein kinase, an important role in agonist-promoted receptor desensitization, coordinated regulatory mechanism involving sequential depalmitoylation and phosphorylation of the beta2-AR by the two kinases |
2.7.11.15 | ATP + beta-adrenergic receptor |
agonist-occupied form of the receptor |
2.7.11.15 | ATP + beta-adrenergic receptor |
involved in homologous desensitization of beta-adrenergic receptor |