EC Number   |
Natural Substrates |
|---|
    1.3.1.70 | more |
brassicasterols have regulatory function in the plants concerning growth and development, the enzyme is up-regulated by several growth-promoting hormones including brassinolide and auxin, overview |
| 1.3.1.70 | more |
enzyme is involved in de novo synthesis of progesterone from lanosterol via cholesterol, pathway overview |
| 1.3.1.70 | more |
enzyme plays a key role in sterol biosynthesis |
| 1.3.1.70 | more |
enzyme plays a key role in sterol biosynthesis, sterol content in vivo |
| 1.3.1.70 | more |
enzyme-deficiency causes the lethal autosomal recessive HEM/Greenberg skeletal dysplasia, characterized by short limbs, fetal hydrops, abnormal chondro-osseous calcification |
| 1.3.1.70 | more |
C14SR is encoded by the TM7SF2 gene. TM7SF2 but not LBR, gene expression is regulated by cell sterol levels in HepG2 (human) and H-35 (rat) hepatoma cells. Primary role of C14SR in human cholesterol biosynthesis |
| 1.3.1.70 | more |
role of LBR in the cholesterol biosynthesis pathway is unclear |
