EC Number |
Natural Substrates |
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1.2.1.12 | more |
the overproducing transformant grows faster and more efficient than the wild-type strain |
1.2.1.12 | more |
the isoproteins TLAb-a and TLAb-2 change depending on the cell growth phase, the carbon source and sodium chloride shock |
1.2.1.12 | more |
high-affinity binding of cAMP to D-glyceraldehyde 3-phosphate dehydrogenase may significantly reduce intracellular cAMP |
1.2.1.12 | more |
activity of isoenzyme 2 increases during postembryonic development |
1.2.1.12 | more |
enzyme is regulated by ATP and by D-glyceraldehyde 3-phosphate |
1.2.1.12 | more |
importance of the enzyme in glucose catabolism. Activity is reduced severalfold after growth on gluconeogenic substrates such as citrate compared to growth on glucose |
1.2.1.12 | more |
classical glycolytic protein involved exclusively in cytosolic energy production |
1.2.1.12 | more |
hypoxia upregulates the glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase in endothelial cells through a 5'-hypoxic regulatory element. Cell-specific patterns of HIF-1alpha and HIF-2alpha expression lead to cell-specific gene upregulation during hypoxia |
1.2.1.12 | more |
NADH-reductive stress in Saccharomyces cerevisiae induces the expression of the minor isoform of glyceraldehyde-3-phosphate dehydrogenase, TDH1 |
1.2.1.12 | more |
oxidation of GAPDH could be the signal for binding with nucleic acids and for change of quarternary structure. Theses events could facilitate GAPDH functioning in DNA reparation and tRNA transportation during oxidative stress |