EC Number |
Inhibitors |
Structure |
---|
4.3.3.1 | 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetraacetic acid |
- |
|
4.3.3.1 | 2,4,6-Trinitrobenzenesulfonic acid |
modification of amino group, 4-nitrophenyl-3-ketovalidamine protect, no protection by 4-nitrophenylvalidamine |
|
4.3.3.1 | 4-nitroaniline |
inhibition at low concentration |
|
4.3.3.1 | Co2+ |
at 1 mM, 37.4% inhibition |
|
4.3.3.1 | Cu2+ |
at 1 mM, 13.5% inhibition |
|
4.3.3.1 | diethyldicarbonate |
modification of histidine residues, pH-dependent, hydroxylamine restores, substrates protect, no protection by 4-nitrophenyl-3-keto-1-epivalidamine, 4-nitrophenyl-beta-D-3-ketoglucoside, 4-nitrophenylvalidamine, 4-nitrophenyl-alpha-D-glucoside, methyl-alpha-D-glucoside, EGTA or CaCl2 |
|
4.3.3.1 | EDTA |
i.e. ethylenediamine tetra acetic acid, at 1 mM, 37°C, for 20 min., 100% inhibition, Ca2+ reverses, not Mg2+ |
|
4.3.3.1 | EGTA |
Ca2+ reverses; i.e. ethyleneglycol bis(beta-aminoethylether)-N,N'-tetraacetic acid, at 1 mM, 37°C, for 20 min., 100% inhibition |
|
4.3.3.1 | EGTA |
Ca2+ reverses |
|
4.3.3.1 | La3+ |
at 1 mM, 97.4% inhibition |
|