EC Number   |
Inhibitors |
Structure |
|---|
   3.1.3.74 | 2,2'-dithiodipyridine |
0.005 mM, 50% inhibition |
   |
| 3.1.3.74 | 2-ethyl-5-phenylisoxazolium-3'-sulfonate |
0.25 mM, 5 min at 22°C, 60% loss of activity, inactivates in a concentration- and time-dependent manner, which follows pseudo-first-order kinetics, pyridoxal 5-phosphate, pyridoxine 5-phosphate or phosphate protects |
|
| 3.1.3.74 | 2-ethyl-5-phenylisoxazolium-3'-sulfonate |
inhibition is potentiated by MgCl2 |
|
| 3.1.3.74 | 4,4'-dithiodipyridine |
0.005 mM, 50% inhibition |
|
| 3.1.3.74 | 4-pyridoxic acid 5'-phosphate |
very effective inhibitor, 0.02 mM, 50% inhibition of pyridoxine 5-phosphate hydrolysis |
|
| 3.1.3.74 | 5,5'-dithiobis(2-nitrobenzoate) |
inhibition is potentiated by MgCl2 |
|
| 3.1.3.74 | 5,5'-dithiobis(2-nitrobenzoate) |
- |
|
| 3.1.3.74 | 5,5'-dithiobis(2-nitrobenzoic acid) |
50 nM, 50% inhibition, incorporation of 1 mol per mol of subunit leads to complete inactivation, phosphate or dithiothreitol protects |
|
| 3.1.3.74 | Ca2+ |
competitive inhibition versus Mg2+, noncompetitive versus substrate |
|
| 3.1.3.74 | Cd2+ |
- |
|
