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EC Number
Inhibitors
Commentary
Structure
3.1.21.10
anti-Endo VII antibodies
Endo X3
3.1.21.10
Ca2+
strong inhibition
3.1.21.10
Cds1
the DNA replication checkpoint kinase Cds1 negatively regulates Mus81/Eme1 to preserve genomic integrity when replication is perturbed
3.1.21.10
EDTA
comple inhibition
3.1.21.10
KCl
reduces activity 10fold at a concentration of 200 mM
3.1.21.10
potassium glutamate
reduces activity 10fold at a concentration of 200 mM
3.1.21.10
RuvA
inhibits cleavage of certain DNA substrates
3.1.21.10
WRWYCR
inhibits junction cleavage
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