EC Number   |
Inhibitors |
Structure |
|---|
   2.7.3.3 | (2S)-2-[[2-[[(2R)-2-[(2-phenoxyacetyl)amino]-3-phenylpropanoyl]amino]acetyl]amino]propanoic acid |
ZINC12654467, probably competitive inhibitor identified by in silico screening |
 |
| 2.7.3.3 | 2-oxoglutarate |
the enzyme activity is inhibited by 10 mM 2-oxoglutarate |
  |
| 2.7.3.3 | 2-oxoglutarate |
the enzyme activity is inhibited at 10-200 mM |
|
| 2.7.3.3 | 4-[[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl]-6,8-dimethyl-chromen-2-one |
ZINC20412486, probably competitive inhibitor identified by in silico screening |
|
| 2.7.3.3 | 5,5'-dithiobis(2-nitrobenzoic acid) |
- |
|
| 2.7.3.3 | 5,5'-dithiobis-(2-nitrobenzoic acid) |
modification and inactivation course with DTNB and the reactivation course of DTNB-modified enzyme. Modified enzyme can be reactivated by an excess concentration of dithiothreitol in a monophasic kinetic course |
|
| 2.7.3.3 | 5,5'-dithiobis-2-nitrobenzoic acid |
- |
|
| 2.7.3.3 | 5,7-dihydroxy-2-phenyl-6,8-bis(1-piperidylmethyl)chromen-4-one |
i.e. ZINC08836734, probably competitive inhibitor identified by in silico screening |
|
| 2.7.3.3 | Ag+ |
dose-dependent, reversible, non-competitive inhibition, complete inhibition at 0.1 mM Ag+ |
|
| 2.7.3.3 | agmatine |
5fold higher concentration than L-Arg, 20% inhibition |
|
