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EC Number
Inhibitors
Commentary
Structure
2.7.2.8
2-oxoglutarate
complete inhibition at 0.5 mM
2.7.2.8
ADP
-
2.7.2.8
ADP
inhibitor of complex formation with PII protein
2.7.2.8
arginine
feedback regulation of enzyme and N-acetylglutamate synthase is mutually interdependent, enzymes form a complex
2.7.2.8
arginine
pH-optimum for inhibition is 7.5
2.7.2.8
arginine
allosteric enzyme which is inhibited by arginine
2.7.2.8
arginine
enzyme has no allosteric properties and its activity is influenced neither by arginine nor by any of the intermediates of the arginine biosynthetic pathway
2.7.2.8
arginine
feedback inhibition is markedly dependent on pH, above pH 9 no inhibition
2.7.2.8
arginine
1 mM, 96% inhibition
2.7.2.8
arginine
feedback inhibition
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