EC Number   |
Inhibitors |
Structure |
|---|
   2.5.1.53 | (2,4-Dihydroxypyrimidin-1-yl)-L-alanine |
i.e. willardiine or 3-(uracil-1-yl)-L-alanine, 30 mM, 84% inhibition of willardiine synthesis and 96% inhibition of isowillardiine synthesis |
   |
| 2.5.1.53 | (2,4-Dihydroxypyrimidin-3-yl)-L-alanine |
i.e. isowillardiine or 3-(uracil-3-yl)-L-alanine, 30 mM produces 75% inhibition of willardiine synthesis and 93% inhibition of synthesis of isowillardiine |
|
| 2.5.1.53 | hydroxylamine |
100 mM, complete |
|
| 2.5.1.53 | KCN |
100 mM, complete |
|
| 2.5.1.53 | PCMB |
0.001 mM, about 90% inhibition |
|
| 2.5.1.53 | pyridoxal 5'-phosphate |
activation at 0.06 mg/ml |
|
| 2.5.1.53 | pyridoxal 5'-phosphate |
0.25 mg/ml, 12% inhibition of willardine synthase and 4% inhibition of isowillardine synthase; activation at 0.06 mg/ml |
|
| 2.5.1.53 | pyridoxal 5'-phosphate |
above 0.1 mM |
|
| 2.5.1.53 | Tris-HCl buffer |
- |
|
| 2.5.1.53 | Uracil |
- |
|
