EC Number |
Inhibitors |
Structure |
---|
2.1.1.2 | 3-deaza-S-adenosyl-L-homocysteine |
competitive with S-adenosylmethionine |
|
2.1.1.2 | 3-deaza-S-adenosyl-L-homocysteine |
- |
|
2.1.1.2 | DTNB |
2 mol DTNB per mol enzyme causes complete inactivation |
|
2.1.1.2 | glutathione |
oxidized form, S-adenosylmethionine protects against inactivation |
|
2.1.1.2 | glutathione |
readily reactivated by reduced glutathione, substrates do not protect against inactivation, guanidinoacetate together with sinefungin protects against inactivation, can be reactivated with thiol compounds |
|
2.1.1.2 | guanidine |
- |
|
2.1.1.2 | iodoacetate |
- |
|
2.1.1.2 | more |
complete and irreversible inactivation by ultraviolet irradiation |
|
2.1.1.2 | N-ethylmaleimide |
irreversible |
|
2.1.1.2 | p-chloromercuribenzoate |
complete inhibition at 1 mM, reversible by addition of glutathione |
|