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EC Number
Activating Compound
Commentary
Reference
1.1.1.141
17beta-estradiol
slight activation
285939
1.1.1.141
corticosterone
4fold activation
285931
1.1.1.141
cortisone
5fold activation
285931
1.1.1.141
cyclooxygenase-1 inhibitors
selective or not
670734
1.1.1.141
dexamethasone
10fold activation
285931
1.1.1.141
dihydrotestosterone
-
285939
1.1.1.141
erlotinib
epidermal growth factor receptor tyrosine kinase inhibitor, trreatment of cells increases the expression of the enzyme in a subset of non-small-cell lung cancer lines
685947
1.1.1.141
estradiol
2fold activation
285931
1.1.1.141
more
12-O-tetradecanoylphorbol-13-acetate induces the synthesis of 15-PGDH but inhibits the enzyme activity a protein kinase C mediated mechanism
285931
1.1.1.141
more
15-PGDH expression is increased by hepatocyte nuclear factor 3beta in lung cancer cells
685958
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