EC Number |
Activating Compound |
Reference |
---|
2.3.1.8 | 1,3-dimercaptopropanol |
activates at 0.01 M |
487515 |
2.3.1.8 | cysteine |
activates at 0.01 M |
487515 |
2.3.1.8 | dithiothreitol |
maxmimum activity in the presence of 1 mM dithiothreitol |
736033 |
2.3.1.8 | hydrogen sulfide |
activates at 0.01 M |
487515 |
2.3.1.8 | more |
not significant efects: NADH, ATP, phosphoenol pyruvate and aspartate, even at concentrations as high as 10 mM |
720217 |
2.3.1.8 | NH4Cl |
3fold stimulation at 40 mM. No significant increase in activity above 40 mM |
674792 |
2.3.1.8 | NH4Cl |
maximal stimulation at 40 mM, 3fold |
674792 |
2.3.1.8 | PPIB |
cytoplasmic cytophilin, interaction with phosphate acetyltransferase leads to enhanced activity and alteration in Km value. PPIase activity is not essential for these interactions, as PPIB F99A active site mutant still interacts with phosphate acetyltransferase, but PPIB activity is responsible for the observed phosphate acetyltransferase activity enhancement |
720425 |
2.3.1.8 | pyruvate |
- |
487532 |
2.3.1.8 | pyruvate |
156% of activation at 5 mM |
720217 |