4.3.1.4Gene ontology ID
GO:0030412
Definition
Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+)
Comment
Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.
Synonyms
1. 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)
2. 5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)
3. formiminotetrahydrofolate cyclodeaminase activity
References
1. EC 4.3.1.42. RHEA: 22736
3. KEGG REACTION: R02302
4. MetaCyc 4.3.1.4-RXN5. Reactome: R-HSA-70920 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate"
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